Disposable Drug Delivery Iontophoresis Pad

B2B disposable iontophoresis pads. Engineered with calibrated Ag/AgCl traces and precise fluid reservoirs to manage current density and prevent chemical burns during electro-osmotic drug delivery.

This disposable pad is a transdermal drug delivery matrix that utilizes continuous direct current (DC) to facilitate the migration of ionized medication across the stratum corneum. Instead of relying on slow, passive absorption, the substrate employs the principles of electrical repulsion (electromigration) and solvent flow (electro-osmosis) to drive active pharmacological agents (such as dexamethasone) directly into localized target tissues. We supply these non-invasive delivery blanks to B2B clinical distributors and digital therapeutics hardware OEMs.

The operational kit consists of two physical components: an active delivery electrode and a dispersive return electrode. The active pad integrates a highly absorbent non-woven fiber matrix positioned directly beneath a screen-printed Silver/Silver Chloride (Ag/AgCl) trace. When clinicians inject liquid medication, the matrix wicks the fluid evenly, transforming the pad into an active electrolyte reservoir. Applying a specific DC milliampere load creates an electrical vector that repels like-charged drug molecules downward. To maintain a safe current density, the geometric surface area of the Ag/AgCl trace is mathematically calibrated against the reservoir's volumetric capacity. Production lines operate under ISO 13485 protocols. MOQ for printed bags is 20,000 units.

• Ag/AgCl pH Buffering Limitation 

  Passing continuous direct current through human tissue and water triggers electrolysis, aggressively generating hydrogen (H+) or hydroxyl (OH-) ions. Unchecked, this rapid pH shift causes severe chemical burns. Standard carbon pads offer zero protection against this reaction. This substrate deploys a sacrificial Ag/AgCl printed layer. During the therapy cycle (typically 40 to 80 mA-min), the silver elements chemically react with the accumulated ions to neutralize the fluid boundary layer. This buffering maintains the pH near physiological levels until the specified mA-min dose is achieved. 

   

• Current Density Flattening

  The effectiveness and safety of iontophoresis depend strictly on distributing the current evenly across the entire surface of the medication pool. If the current funnels directly down from the lead wire (creating a density spike > 0.5 mA/cm²), it drills a high-intensity electrical path into the skin, burning the patient. The internal trace routing of this pad is engineered to force the incoming electrons to scatter laterally to the extreme edges of the reservoir before pushing downwards into the fluid, rendering a mathematically flat current distribution curve. 

   

• Hydrophobic Fluid Containment

  When a clinician injects 2.0cc of fluid into a pad, that liquid must stay entirely within the active delivery zone. If the capillary action of the matrix bleeds medication outward into the adhesive border, it creates a conductive liquid bridge across the skin surface. This causes the current to travel sideways (short-circuiting) instead of downward into the tissue. The central reservoir is bounded by an aggressive, hydrophobic closed-cell PE foam dam that strictly halts lateral fluid migration and locks the electrical vector vertically.

• Volumetric Reservoir Sizing: The physical capacity of the non-woven matrix can be engineered via specific die-cut dimensions to hold exact volumes (e.g., 1.5cc, 2.0cc, 3.0cc) matching specific clinical vial sizes, preventing under-dosing or overflow. 

• Logistics Routing: The specialized Ag/AgCl screen printing and reservoir lamination operate in our China facilities. Individual barrier-pouch sealing (to prevent silver oxidation) and international bulk packing are routed through our Vietnam hub to manage supply chain continuity and optimize global medical tariffs.

• Systems: Physical assembly and active trace printing are executed strictly within audited ISO 13485:2016 frameworks. 

• Biocompatibility: The fluid-containment adhesive and dispersive gel layers are validated against ISO 10993-5 (Cytotoxicity) and ISO 10993-10 (Sensitization).

B2B procurement teams and clinical hardware OEMs can request unbranded blanks and current density mapping reports to verify pH buffering stability. 

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